Duration and distance of exposure are important predictors of transmission among community contacts of Ontario SARS cases
Identifieur interne : 003725 ( Main/Exploration ); précédent : 003724; suivant : 003726Duration and distance of exposure are important predictors of transmission among community contacts of Ontario SARS cases
Auteurs : E. Rea [Canada] ; J. Laflèche [Canada] ; S. Stalker [Canada] ; B. K. Guarda [Canada] ; H. Shapiro [Canada] ; I. Johnson [Canada] ; S. J. Bondy [Canada] ; R. Upshur [Canada] ; M. L. Russell [Canada] ; M. Eliasziw [Canada]Source :
- Epidemiology and Infection [ 0950-2688 ] ; 2007.
Abstract
We report attack rates and contact-related predictors among community contacts of severe acute respiratory syndrome (SARS) cases from the 2003 Toronto-area outbreak. Community contact data was extracted from public health records for single, well-defined exposures to a SARS case. In total, 8662 community-acquired exposures resulted in 61 probable cases; a crude attack rate of 0·70% [95% confidence interval (CI) 0·54–0·90]. Persons aged 55–69 years were at higher risk of acquiring SARS (1·14%) than those either younger (0·60%) or older (0·70%). In multivariable analysis exposures for at least 30 min at a distance of ⩽1 m increased the likelihood of becoming a SARS case 20·4-fold (95% CI 11·8–35·1). Risk related to duration of illness in the source case at time of exposure was greatest for illness duration of 7–10 days (rate ratio 3·4, 95% CI 1·9–6·1). Longer and closer proximity exposures incurred the highest rate of disease. Separate measures of time and distance from source cases should be added to minimum datasets for the assessment of interventions for SARS and other emerging diseases.
Url:
DOI: 10.1017/S0950268806007771
PubMed: 17217552
PubMed Central: 2870656
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000C49
- to stream Pmc, to step Curation: 000C49
- to stream Pmc, to step Checkpoint: 000F73
- to stream Ncbi, to step Merge: 001831
- to stream Ncbi, to step Curation: 001831
- to stream Ncbi, to step Checkpoint: 001831
- to stream Main, to step Merge: 003868
- to stream Main, to step Curation: 003725
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Duration and distance of exposure are important predictors of transmission among community contacts of Ontario SARS cases</title><author><name sortKey="Rea, E" sort="Rea, E" uniqKey="Rea E" first="E." last="Rea">E. Rea</name><affiliation wicri:level="1"><nlm:aff id="aff001">Toronto Public Health, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto Public Health, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lafleche, J" sort="Lafleche, J" uniqKey="Lafleche J" first="J." last="Laflèche">J. Laflèche</name><affiliation wicri:level="1"><nlm:aff id="aff001">Toronto Public Health, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto Public Health, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Stalker, S" sort="Stalker, S" uniqKey="Stalker S" first="S." last="Stalker">S. Stalker</name><affiliation wicri:level="1"><nlm:aff id="aff002">York Region Health Services, Newmarket, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>York Region Health Services, Newmarket, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Guarda, B K" sort="Guarda, B K" uniqKey="Guarda B" first="B. K." last="Guarda">B. K. Guarda</name><affiliation wicri:level="1"><nlm:aff id="aff003">Simcoe Muskoka District Health Unit, Barrie, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Simcoe Muskoka District Health Unit, Barrie, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Shapiro, H" sort="Shapiro, H" uniqKey="Shapiro H" first="H." last="Shapiro">H. Shapiro</name><affiliation wicri:level="1"><nlm:aff id="aff004">Region of Peel Public Health, Brampton, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Region of Peel Public Health, Brampton, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Johnson, I" sort="Johnson, I" uniqKey="Johnson I" first="I." last="Johnson">I. Johnson</name><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bondy, S J" sort="Bondy, S J" uniqKey="Bondy S" first="S. J." last="Bondy">S. J. Bondy</name><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Upshur, R" sort="Upshur, R" uniqKey="Upshur R" first="R." last="Upshur">R. Upshur</name><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Russell, M L" sort="Russell, M L" uniqKey="Russell M" first="M. L." last="Russell">M. L. Russell</name><affiliation wicri:level="4"><nlm:aff id="aff006">Department of Community Health Sciences, University of Calgary, Alberta, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Community Health Sciences, University of Calgary, Alberta</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Eliasziw, M" sort="Eliasziw, M" uniqKey="Eliasziw M" first="M." last="Eliasziw">M. Eliasziw</name><affiliation wicri:level="4"><nlm:aff id="aff006">Department of Community Health Sciences, University of Calgary, Alberta, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Community Health Sciences, University of Calgary, Alberta</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff007">Department of Clinical Neurosciences, University of Calgary, Alberta, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Neurosciences, University of Calgary, Alberta</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">17217552</idno><idno type="pmc">2870656</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870656</idno><idno type="RBID">PMC:2870656</idno><idno type="doi">10.1017/S0950268806007771</idno><date when="2007">2007</date><idno type="wicri:Area/Pmc/Corpus">000C49</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000C49</idno><idno type="wicri:Area/Pmc/Curation">000C49</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000C49</idno><idno type="wicri:Area/Pmc/Checkpoint">000F73</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000F73</idno><idno type="wicri:Area/Ncbi/Merge">001831</idno><idno type="wicri:Area/Ncbi/Curation">001831</idno><idno type="wicri:Area/Ncbi/Checkpoint">001831</idno><idno type="wicri:doubleKey">0950-2688:2007:Rea E:duration:and:distance</idno><idno type="wicri:Area/Main/Merge">003868</idno><idno type="wicri:Area/Main/Curation">003725</idno><idno type="wicri:Area/Main/Exploration">003725</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Duration and distance of exposure are important predictors of transmission among community contacts of Ontario SARS cases</title><author><name sortKey="Rea, E" sort="Rea, E" uniqKey="Rea E" first="E." last="Rea">E. Rea</name><affiliation wicri:level="1"><nlm:aff id="aff001">Toronto Public Health, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto Public Health, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Lafleche, J" sort="Lafleche, J" uniqKey="Lafleche J" first="J." last="Laflèche">J. Laflèche</name><affiliation wicri:level="1"><nlm:aff id="aff001">Toronto Public Health, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Toronto Public Health, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Stalker, S" sort="Stalker, S" uniqKey="Stalker S" first="S." last="Stalker">S. Stalker</name><affiliation wicri:level="1"><nlm:aff id="aff002">York Region Health Services, Newmarket, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>York Region Health Services, Newmarket, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Guarda, B K" sort="Guarda, B K" uniqKey="Guarda B" first="B. K." last="Guarda">B. K. Guarda</name><affiliation wicri:level="1"><nlm:aff id="aff003">Simcoe Muskoka District Health Unit, Barrie, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Simcoe Muskoka District Health Unit, Barrie, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Shapiro, H" sort="Shapiro, H" uniqKey="Shapiro H" first="H." last="Shapiro">H. Shapiro</name><affiliation wicri:level="1"><nlm:aff id="aff004">Region of Peel Public Health, Brampton, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Region of Peel Public Health, Brampton, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Johnson, I" sort="Johnson, I" uniqKey="Johnson I" first="I." last="Johnson">I. Johnson</name><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Bondy, S J" sort="Bondy, S J" uniqKey="Bondy S" first="S. J." last="Bondy">S. J. Bondy</name><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Upshur, R" sort="Upshur, R" uniqKey="Upshur R" first="R." last="Upshur">R. Upshur</name><affiliation wicri:level="4"><nlm:aff id="aff005">Public Health Sciences, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Public Health Sciences, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Russell, M L" sort="Russell, M L" uniqKey="Russell M" first="M. L." last="Russell">M. L. Russell</name><affiliation wicri:level="4"><nlm:aff id="aff006">Department of Community Health Sciences, University of Calgary, Alberta, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Community Health Sciences, University of Calgary, Alberta</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Eliasziw, M" sort="Eliasziw, M" uniqKey="Eliasziw M" first="M." last="Eliasziw">M. Eliasziw</name><affiliation wicri:level="4"><nlm:aff id="aff006">Department of Community Health Sciences, University of Calgary, Alberta, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Community Health Sciences, University of Calgary, Alberta</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="aff007">Department of Clinical Neurosciences, University of Calgary, Alberta, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Clinical Neurosciences, University of Calgary, Alberta</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author></analytic><series><title level="j">Epidemiology and Infection</title><idno type="ISSN">0950-2688</idno><idno type="eISSN">1469-4409</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>SUMMARY</title><p>We report attack rates and contact-related predictors among community contacts of severe acute respiratory syndrome (SARS) cases from the 2003 Toronto-area outbreak. Community contact data was extracted from public health records for single, well-defined exposures to a SARS case. In total, 8662 community-acquired exposures resulted in 61 probable cases; a crude attack rate of 0·70% [95% confidence interval (CI) 0·54–0·90]. Persons aged 55–69 years were at higher risk of acquiring SARS (1·14%) than those either younger (0·60%) or older (0·70%). In multivariable analysis exposures for at least 30 min at a distance of ⩽1 m increased the likelihood of becoming a SARS case 20·4-fold (95% CI 11·8–35·1). Risk related to duration of illness in the source case at time of exposure was greatest for illness duration of 7–10 days (rate ratio 3·4, 95% CI 1·9–6·1). Longer and closer proximity exposures incurred the highest rate of disease. Separate measures of time and distance from source cases should be added to minimum datasets for the assessment of interventions for SARS and other emerging diseases.</p></div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Alberta</li><li>Ontario</li></region><settlement><li>Calgary</li><li>Toronto</li></settlement><orgName><li>Université de Calgary</li><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><noRegion><name sortKey="Rea, E" sort="Rea, E" uniqKey="Rea E" first="E." last="Rea">E. Rea</name></noRegion><name sortKey="Bondy, S J" sort="Bondy, S J" uniqKey="Bondy S" first="S. J." last="Bondy">S. J. Bondy</name><name sortKey="Eliasziw, M" sort="Eliasziw, M" uniqKey="Eliasziw M" first="M." last="Eliasziw">M. Eliasziw</name><name sortKey="Eliasziw, M" sort="Eliasziw, M" uniqKey="Eliasziw M" first="M." last="Eliasziw">M. Eliasziw</name><name sortKey="Guarda, B K" sort="Guarda, B K" uniqKey="Guarda B" first="B. K." last="Guarda">B. K. Guarda</name><name sortKey="Johnson, I" sort="Johnson, I" uniqKey="Johnson I" first="I." last="Johnson">I. Johnson</name><name sortKey="Lafleche, J" sort="Lafleche, J" uniqKey="Lafleche J" first="J." last="Laflèche">J. Laflèche</name><name sortKey="Rea, E" sort="Rea, E" uniqKey="Rea E" first="E." last="Rea">E. Rea</name><name sortKey="Russell, M L" sort="Russell, M L" uniqKey="Russell M" first="M. L." last="Russell">M. L. Russell</name><name sortKey="Shapiro, H" sort="Shapiro, H" uniqKey="Shapiro H" first="H." last="Shapiro">H. Shapiro</name><name sortKey="Stalker, S" sort="Stalker, S" uniqKey="Stalker S" first="S." last="Stalker">S. Stalker</name><name sortKey="Upshur, R" sort="Upshur, R" uniqKey="Upshur R" first="R." last="Upshur">R. Upshur</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003725 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003725 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:2870656
|texte= Duration and distance of exposure are important predictors of transmission among community contacts of Ontario SARS cases
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:17217552" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |